Marble Burying Problems

The marble burying behavior test is an acute test.

Marble burying problems.

1 3 since the bulk of this work was done using female mice the 1 1 ns finding that males have the same propensity to bury marbles shows 1 5 ns that the behavior is not peculiar to. While widely used there is significant controversy over the interpretation of its results. However some investigators incorporate the sub acute treatment regimen as an essential component for screening anti compulsive agents. It has also been proposed that the test may have predictive validity for the screening of novel antidepressants 12 15 anxiolytics 15 16 and antipsychotics 17 19.

Marble burying the marble burying test is a useful model of neophobia 1 anxiety 1 7 and obsessive compulsive behavior 8 11. The marble burying test is commonly used to quantify anxiety obsessive compulsive or repetitive behaviour in rodents 1 3 performance on the marble burying test is also associated with general digging behaviour 4 7 and so the underlying construct being measured is still unclear regardless the typical protocol places 10 25 marbles in a cage containing sawdust or similar. Marble burying is an animal model used in scientific research to depict anxiety or obsessive compulsive disorder ocd behavior. The 1 3 ns finding that marble burying was constant across several exposures at different times of day suggests that burying behavior has no clear diurnal pattern.